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...Boldly Attacking Alzheimer’s from Every Angle
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From Our Founders

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Leonard A. Lauder
Headshot of Ronald S. Lauder wearing a suit and tie
Ronald S. Lauder

From Our Executive Leadership

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Howard Fillit, MD
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Mark Roithmayr
Watch Our 25th Anniversary Video
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$273
M
INVESTED IN SCIENCE
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731
PROJECTS FUNDED
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110
BIOTECH COMPANIES FUNDED
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Leading Therapeutics Development in New Directions

At the ADDF, we are among the world’s leaders in identifying cutting-edge ideas and investing in breakthrough research to forge the best path to effective Alzheimer’s therapeutics.

We know successful treatment will ultimately rely on a combination of therapies that work against a range of targets informed by the biology of aging, providing personalized approaches for each patient. We are dedicated to driving research and resources forward to achieve this goal.

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Fast-Tracking Diagnostics Development

More accurate, accessible, and affordable tools for the early detection and diagnosis of Alzheimer’s are essential to defeat this devastating disease. As in everything we do, we are taking a 360-degree approach, working diligently to ensure every potential drug target has corresponding biomarkers.

Our $100 million Diagnostics Accelerator initiative, which launched its second phase last year, has united preeminent philanthropists and renowned scientists in the quest to speed development of these critical tools. We are proud to have been one of the most significant supporters of this crucial research in 2023.

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Revolutionizing Alzheimer’s Prevention

Prevention is a key pillar in the ADDF’s fight against Alzheimer’s disease. Delaying onset by just five years may result in up to 50% lower disease prevalence.

This year, we launched a first-of-its-kind Precision Prevention Partnership, which will look at therapeutics and lifestyle interventions in tandem to revolutionize the way we treat and prevent this disease. We also continued to play a leading role in providing resources on the latest brain health findings and lifestyle recommendations, vetted by our team of in-house neuroscientists.

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Thought Leadership

In 2023, the ADDF continued to expand our global presence, using our platform at conferences and summits across the world to shape the direction of the field and guide resources in the right direction to accelerate research and get treatments into the hands of patients as quickly as possible. We were honored to be included among the top authorities in the medical community, with Dr. Howard Fillit and Mark Roithmayr speaking alongside the Milken Institute’s Michael Milken, Gates Ventures’ Niranjan Bose, and Eli Lilly’s Anne White to name just a few.

We also convened several of the most exciting voices in Alzheimer’s research at our Tomorrow’s Breakthroughs Today Scientific Symposium Series, founded in partnership with Heidi and Tom McWilliams, which each year features three world-class scientists discussing the path toward new treatments for Alzheimer’s and other dementias.

2023 Thought Leadership & Conferences

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Berkeley, CA
Defeating Dementia Symposium
April 2023
San Francisco, CA
J.P. Morgan Healthcare Conference
January 2023
Los Angeles, CA
Milken Global Conference
May 2023
Boston, MA
BIO Convention
June 2023
CTAD Conference
October 2023
Palm Beach, FL
Tomorrow’s Breakthroughs Today Scientific Symposium Series
January 2023
April 2023
London, England
World Dementia Council Summit
April 2023
Amsterdam, Netherlands
AAIC Conference
July 2023
Gothenburg, Sweden
AD/PD Conference
March 2023
Stockholm, Sweden
ADDF Visit to Miia Kivipelto’s Lab
March 2023

Recognizing Revolutionary Ideas

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Rhoda Au, PhD, MBA

Recognizing Revolutionary Ideas

Each year, the ADDF awards the Melvin R. Goodes Prize for Excellence in Alzheimer’s Drug Development to a scientist whose cutting-edge work based on the biology of aging is making a significant and lasting impact on the field.

Our 2023 winner, Rhoda Au, PhD, MBA, Professor of Anatomy and Neurobiology at the Boston University Chobanian and Avedisian School of Medicine, was selected in recognition of her pioneering work creating digital biomarkers that may help detect warning signs of Alzheimer’s earlier than ever.

Dr. Au’s research leverages technology from smartphones and tablets to collect data on Alzheimer’s-related characteristics, which can help to detect the disease 20 to 30 years before symptoms present. The data is used to create digital profiles that can differentiate between people with stable cognition, cognitive decline, and dementia. Digital biomarkers like those being developed by Dr. Au will make it easier and more accessible to monitor for warning signs of dementia, enabling patients to be monitored in their own homes rather than having to commute to a physician’s office.

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Dr. Au’s research leverages technology from smartphones and tablets to collect data on Alzheimer’s-related characteristics, which can help to detect the disease 20 to 30 years before symptoms present. The data is used to create digital profiles that can differentiate between people with stable cognition, cognitive decline, and dementia. Digital biomarkers like those being developed by Dr. Au will make it easier and more accessible to monitor for warning signs of dementia, enabling patients to be monitored in their own homes rather than having to commute to a physician’s office.

Past Goodes Prize Winners

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2022
Miranda Orr, PhD
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2021
Miia Kivipelto, MD, PhD
Headshot of Jerri Rook smiling
2020
Jerri Rook, PhD
Headshot of Jeffrey Cummings smiling
2019
Jeffrey L. Cummings, MD, ScD
Headshot of Michela Gallagher smiling
2018
Michela Gallagher, PhD
Headshot of Roberta Diaz Brinton smiling
2017
Roberta Diaz Brinton, PhD
Headshot of Daniel Watterson smiling
2016
Daniel Martin Watterson, PhD
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2015
Frank M. Longo, MD, PhD

Stewardship

Sixth Annual Hope on the Horizon Palm Beach Dinner

The ADDF kicked off the celebration of our 25th anniversary by welcoming supporters to our annual Palm Beach event. The evening honored Bonnie Lautenberg as the recipient of the 2023 Hope on the Horizon Award for 15 years of leadership and outstanding support of the ADDF’s mission.

Stewardship

Sixth Annual Memories Matter

The night of hope and optimism hosted at the American Museum of Natural History featured a special appearance from Tony-nominated actor and singer Jarrod Spector, who delivered a heartwarming and inspiring performance, and a hopeful speech from Travis and Mark Macy, elite endurance athletes who participated in the World’s Toughest Race Eco-Challenge.

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Ian Ginsberg, Stephanie Ginsberg, Wendy Wilshin, and Ron Dickerman standing next to each otherDoug Winshall, Wendi Winshall, Hope Altheim, and Marc Altheim standing next to each otherMark Macy, Travis Macy, and Josh Lauder in suits standing next to each other
Mark Macy, Travis Macy, and Josh Lauder in suits standing next to each other

Stewardship

Thirteenth Annual Great Ladies Luncheon and Fashion Show

Our annual celebration of science and fashion honored philanthropist Amy Baier with the 2023 Great Ladies Award and entrepreneur and restaurateur of Café Milano fame Franco Nuschese with the 2023 Estelle Gelman Award. The program also featured a special fashion show of designs by AKRIS in collaboration with our fashion partner Saks.

Stewardship

Sixteenth Annual Connoisseur’s Dinner

Held at Sotheby’s New York, the event celebrated Leonard A. Lauder, Ronald S. Lauder, William Lauder, Gary Lauder, Aerin Lauder Zinterhofer, and Jane Lauder in honor of their historic $200 million gift to the ADDF. This incredible multigenerational commitment ensures the ADDF will be able to fulfill our mission and change the way the world ages.

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William Lauder, Jane Lauder, Ronald S. Lauder, Aerin Lauder Zinterhofer, and Gary Lauder dressed in formal attire, standing together at a black tie eventMark Roithmayr, Aerin Lauder Zinterhofer, William Lauder, Jane Lauder, Ronald S. Lauder, Gary Lauder, Paula Zahn, and Howard Fillit dressed in formal attire, standing together at a black tie eventRonald S. Lauder and Paula Zahn sitting on chairs in front of a purple curtain
Ronald S. Lauder and Paula Zahn sitting on chairs in front of a purple curtain

Stewardship

Second Annual House of Purple

Led by the next generation of Alzheimer’s advocates to engage their peers in the cause, the fun and hopeful event honored ADDF Young Professionals Committee (YPC) Membership Committee Lead, Lizzie Toma, with the Outstanding Volunteer Award for her leadership and commitment to the YPC and the ADDF's mission.

Friendship

We are deeply grateful to all those who supported our work in 2023. Your generosity gives us hope for a future without Alzheimer’s disease.

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The ADDF is profoundly grateful to Leonard A. Lauder, Ronald S. Lauder, William Lauder, Gary Lauder, Aerin Lauder Zinterhofer, and Jane Lauder for their historic $200 million gift. Thanks to their visionary philanthropy, every dollar donated to the ADDF goes directly to innovative science.
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Abigail Smul
Daniel Snyder
Solis Betancourt & Sherrill, Inc.
Lisa and Denis Somar
Tina and Sonny
Amy and David Sorkin
The Sosnow Foundation, Inc.
Spotfund Technologies, Inc
Laurie Sprayregen
Bonnie Karl Staffier
Candice Stark
Patricia Steele
Joan Steinberg
Renée Steinberg
Matthew Stenberg
Maria and Bryan Stepanian
Jeffrey M. Stern
Paul Stern
Steven Stern
Jennifer Stiebel
Marian and Jeff Stier
Susan Stolzer
Mindy Strelitz
Fred Sugar
Diane Supinsky
Hayley Susino
Olivia P. Sutter
Betsy and Chip Swerksy
Thomas and Margaret Tan Family Foundation
Karen and Marc Taub
Julie and Marc Tell
Leslie and Andrew Tell
Daniel Termini
Sandra Thackeray
Judith Thorn
Lynn P. Tishman Fund Inc
Rachel and Robby Tobin
Robert Tobin
Robbi Toll
Elisabeth Toma
Totten Family Foundation
Lisa Tuttle
Laura Tyson
Keith Underwood
Gianluigi Vittadini
Mary Walker
Lorraine and Christopher Wallace
Nora Ann Wallace
Daniel E. Warren
Sandra and Stanford Warshawsky
Ellen and David Wasserman
The Waterfall Family Foundation
Watermark at Brooklyn Heights
Tamara Watkins
Jules and Joe Watson
Charlotte C. Weber
Melissa and Michael Weinbaum
William Weinfeld
David N. Weinstein
Caroline and Daniel Werther
West Monroe Partners
Janice Willinger
Seth Wilson
Jillian Winoker
Wendi and Doug Winshall
The Winter Organization
Susanna Wong
Austin Wright
Kara Yacovone
Benjamin Zeliger
Lois Mazer Zelman
Lois and Bruce Zenkel
Robert Zizza
Salvatore J. Zizza
Silvia Zoullas
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Our Boards

The Board of Governors is the principal board of the Corporation with all legal power and authority to manage, oversee, and make decisions regarding the ADDF’s programs and activities. Board members include leaders from government, industry, and the research community who serve as ambassadors for the ADDF and provide strategic oversight and counsel.

ADDF HONORARY CHAIR (RETIRED)
Justice Sandra Day O’Connor
Associate Justice, US Supreme Court
ADDF CO-CHAIRS
Leonard A. Lauder
Chairman Emeritus, The Estée Lauder Companies Inc.
Ronald S. Lauder
Chairman, Clinique Laboratories, LLC
CO-VICE CHAIR AND SECRETARY
Randal Sandler
Director of Client Services and Marketing, Bridgewater Associates
EX OFFICIO
Howard Fillit, MD
Co-Founder and Chief Science Officer, Alzheimer’s Drug Discovery Foundation
CO-VICE CHAIR AND TREASURER
Thomas F. McWilliams
Private Investor, Retired Managing Partner, Court Square Capital Partners
* Honorary Members
In Memoriam
Robert A. Belfer*
Chairman, Belfer Management
Carol Seabrook Boulanger
Partner, Pillsbury, Winthrop, Shaw, and Pittman, LLP
Roberta Diaz Brinton, PhD
Inaugural Director of the Center for Innovation in Brain Science at the University of Arizona, Professor of Pharmacology and Neurology in the College of Medicine, Tucson
Nancy Corzine
President and CEO, Nancy Corzine Inc.
Ric Edelman
Founder, Digital Assets Council of Financial Professionals and Founder, The Truth About Your Future
Lanny Edelsohn, MD
Director, Christiana Care Health Systems, Inc.
Bonnie Pfeifer Evans
Senior Sales Associate, Corcoran Group Real Estate; Co-Trustee, The Charles Evans Foundation
Melvin R. Goodes*
Former Chairman and CEO, Warner-Lambert
Nancy Goodes
Former Executive, Nazareth-Century Mills; Secretary, Melvin R. Goodes Family Foundation, Inc.
Miia Kivipelto, MD, PhD
Professor of Clinical Geriatrics, Karolinska Institutet Center for Alzheimer Research, Senior Geriatrician and Director for Research and Development of Medical Unit Aging, Karolinska University Hospital
Gary M. Lauder
Managing Director, Lauder Partners LLC
Bonnie Englebardt Lautenberg
Photographer and Writer, Bonnie Lautenberg Designs
Laurence C. Leeds, Jr.
Chairman, Buckingham Capital Management, Inc.
Richard C. Mohs, PhD
Chief Science Officer, Global Alzheimer’s Platform Foundation
Sally Susman*
Executive Vice President, Policy, External Affairs and Communications, Pfizer Inc
Beatriz Illescas Putzeys-Claugus
Educator, Sworn Translator, Diplomat, and Philanthropist, Founder, The Foundation for a Better World
Sharon T. Sager, CIMA
Managing Director and Private Wealth Advisor, UBS Private Wealth Management
Alice Shure
Founder and Producer, AMICI Productions LLC; Co-Trustee, The Charles Evans Foundation
Thomas S. (Tad) Smith, Jr
Chief Executive Officer and Director, TheKey
David R. Weinreb
Chief Executive Officer, Weinreb Ventures
Paula Zahn
Host and Executive Producer, Discovery ID’s “On the Case with Paula Zahn,” and WNET’s “NYC Arts”
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The Board of Overseers is an advisory body committed to providing counsel and support to the ADDF Board of Governors and staff. Overseers lend their expertise to advance the ADDF's mission to accelerate the development of drugs to prevent, treat and cure Alzheimer’s disease. Overseers are appointed by and serve at the pleasure of the Board of Governors.

CHAIR
Christopher Johnson
President, Rackson Companies
Bal Agrawal
Founder and Chief Executive Officer, LifeWorx, Inc.; Founder and Chief Executive Officer, Prima Chefs, Inc.
Charles Cangro
Former Principal, Personal Financial Services, Ernst & Young, LLP
Charlie Lefkowitz Crowley
Educational Consultant and Philanthropist
Mitchell D. Eichen, J.D., LL.M.
Founder and Chief Executive Officer, Acertus Capital ManagementFounder and Chief Executive Officer, The MDE Group
Joel Florin
President, Micro Essential Laboratory, Inc.
Dave Gerson
Personal Financial Planning Consultant, Retired Tax Partner Ernst & Young, LLC
Stephanie Ginsberg
Volunteer, Philanthropist; Founder, BCRF Pink Promises Benefit
Allan M. Green, MD, PhD, JD
Allan M. Green Esq., LLC
Gina F. Holzheimer
Vice President, J.P. Morgan Private Bank; Co-Founder and Co-Chair, ADDF Young Professionals Committee
Mitchell Kaneff
Chairman and Chief Executive Officer, Arkay
Josh Lauder
Co-Founder and Co-Chair, ADDF Young Professionals Committee
Elise Gelman Lefkowitz
Philanthropist
Philip Lovett
Founding Partner, Millennium Partners
Julie Medler
Managing Director, Golden Seeds
Justin Meltzer
Real Estate Operations, DLA Piper LLP
Phebe Farrow Port
Senior Vice President, Global Management Strategies and Chief of Staff, Executive Management Initiatives, The Estée Lauder Companies Inc.
Gregory A. Rosica
Partner, Tax, Ernst & Young, LLC
Tom Scanlan
Partner, Spencer Stuart
John H. Scully, CIMA
Senior Managing Director, Head of Private Wealth Advisory, Nuveen Investments
Stephen Toma
Managing Director, VJMS, LLC
Wendy L. Wilshin
Founder and Principal, WLW Designs
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Audited Financials

PDF (532 KB)

Form 990

PDF (972 KB)